产品货号：
Z22938
中文名称：
PAK5/PAK7抗体
英文名称：
Anti-PAK5/PAK7 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PAK5/PAK7 Antibody |
| 指标别名 | KIAA1264;p21 activated kinase 5;p21 activated kinase 7;PAK 5;PAK 7;PAK5;PAK7 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | PAK7 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | PAK5 antibody was raised against a 13 amino acid synthetic peptide from near the center of human PAK5.The immunogen is located within amino acids 240 - 290 of PAK5. |
| 计算分子量 | 81kDa |
| 成分 | PAK5 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | PAK5 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac.They are divided into two groups,the first of which include PAK1,2 and 3,and can be activated by Cdc42/Rac binding.Group 1 PAKs contain an autoinhibitory domain whose activity is regulated by Cdc42/Rac binding.The group 1 PAKs are known to be involved in cellular processes such as gene transcription,apoptosis,and cell morphology and motility.Much less is known about the second group,which includes PAK4,5 and 6.These proteins are not activated by Cdc42/Rac binding.PAK5 was initially identified as a kinase expressed primarily in brain that while possessing a kinase domain and GTPase binding domain similar to PAK4 and PAK6,is completely different from both.Expression of PAK5 in neural based cell lines resulted in neurite outgrowth suggesting that PAK5 may be involved in regulating the cytoskeletal changes necessary for promoting neurite outgrowth.Other experiments suggest that unlike the other PAKs,PAK5 may inhibit apoptosis by phosphorylating the Bcl-2 family member Bad. |
| Uniprot ID | Q9P286 |
| 基因名全称 | P21 protein (Cdc42/Rac)-activated kinase 7 |
| 蛋白名全称 | P21 protein (Cdc42/Rac)-activated kinase 7 |
| 推荐稀释比 | PAK5 antibody can be used for the detection of PAK5 by Western blot at 2 ～ 4μg/mL.Antibody can also be used for immunocytochemistry starting at 2μg/mL.For immunofluorescence start at 10μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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